Head Transplantation in Mouse Model

Orthotopic liver transplantation from cardiac death donors in the mouse: a new model and evaluation of cardiac death time

Objective(s): The goal of this research was to develop a mouse orthotopic liver transplantation (LTx) model from donor-after-cardiac-death (DCD) grafts. Materials and Methods: Mice were randomly assigned to the experimental group or the sham group. The mice in the experimental group were divided into three groups according to the warm ischemia time (WIT) of liver graft: normal LTx, WIT 30 minut...

Vasectomy in Mouse Model Using Electrosurgery Machine

Vasectomy in laboratory animals is a crucial step in the production of surrogate female mice. The surrogate mothers play a key role in successful embryo transfer, most important steps for the production of transgenic animal models, investigation of the preimplantation embryo development, and revitalization of cryopreserved strains. Abdominal and scrotal surgeries are common surgical proce...

spermatogonial stem cell transplantation and subsequent orchidopexy in the bilateral cryptorchid mouse model

objective: testicular cell transplantation has been widely used to investigate the restoration of fertility in rodent models. in this research we apply transplantation as a treatment method in the cryptorchid model and compare this method with orchidopexy, which is the routine treatment for this problem. we studied the controversial effects of treatment on the number of germ cells and other mor...

Mouse Model for Pancreas Transplantation Using a Modified Cuff Technique

Mouse models have several advantages in transplantation research, including easy handling, a variety of genetically well-defined strains, and the availability of the widest range of molecular probes and reagents to perform in vivo as well as in vitro studies. Based on our experience with various murine transplantation models, we developed a heterotopic pancreas transplantation model in mice wit...

Ethical considerations regarding head transplantation